You probably know by now that at SiS, we’re all about science. There is scientific evidence that health supplements work best when taken at particular times. For example, it is often recommended that you take multivitamin supplements in the morning as B Vitamins can be too stimulating for the brain before bed. Water soluble vitamins like B Vitamins and Vitamin C absorb best on an empty stomach, so you should take these around two hours prior to your meal or first thing in the morning. GET TOP TIPS FOR SPORTING PERFORMANCE AND NUTRITION ON OUR BLOG Supplementing can help you reach your fitness goals and enhance your overall well being. Our Performance Multivitamin is the perfect option for endurance athletes looking to meet their nutritional needs, with 19 key vitamins and minerals. These vitamins offer a multitude of benefits to your health, including supporting the normal functioning of the immune system, reducing tiredness and fatigue, maintenance of normal bones and muscle function, and normal protein and glycogen metabolism. Consume up to 1 tablet per day in addition to a balanced diet and a healthy lifestyle. Add one Immune tablet to 500ml of water and let it dissolve. Once prepared consume within 24 hours. In the form of an effervescent tablet, it makes into a low calorie rehydration drink containing vitamin C and Iron Heavy training is known to impact the immune system, suppressing it for 3‐72 hours post-training. This can lead to a higher incidence of upper respiratory tract Infections, impacting an athletes health and their ability to train.

Excessive vitamin intake can suppress the training response. SiS Immune is designed to be at a level which supports athlete health without compromising training benefits. The best isotonic drinks give you sugars for energy so you can fuel for your body. We believe the more efficient formats like gels and powders stand out because they allow you to supplement intra-workout without any problems! Plus, our SiS energy range comes in a variety of flavours, sugar options, and caffeinated or non-caffeinated options to suit your needs. Our Vitamin C tablets are fantastic for maintaining the normal function of your immune system and contribute to the reduction of tiredness and fatigue. Vitamins A, B, C, D and E are important for hair growth, alongside iron and zinc. HEALTH SUPPLEMENTSSiS Immune dosage is designed to be at a level which supports athlete health without compromising training benefits The use of mice has been guided by strict adherence to the protocols (ID# 09-15-2010:SKG/YA; ID# 01-03-2011: SKG/RR), approved specifically for this study, by the Indiana State University Animal Care and Use Committee (IACUC). Female BALB/c mice (6–8 weeks of age) were used for all experiments. Pathogen-free BALB/c mice were bought from Harlan Sprague-Dawley (Indiana, USA), kept in quarantine for two weeks and then relocated to specific mouse facility that is routinely monitored by veterinarians, IACUC and USDA inspectors. These mice were bred and maintained at the animal care facility of Indiana State University. Recommended Usage: After prolonged or intense exercise use one tab in 500ml of water to support immune function as you rehydrate Heavy training is known to impact the immune system, suppressing it for 3-72 hours post-training. This can lead to a higher incidence of upper respiratory tract Infections, impacting an athletes health and their ability to train. Excessive vitamin intake can suppress the training response. SiS Immune is designed to be at a level which supports athlete health without compromising training benefits. SiS Immune is tested under Informed Sport certification. This approach gives you confidence that we pay attention to detail and deliver high quality sports nutrition, whether you are an elite athlete or just trying to keep fit and healthy. After prolonged or intense exercise use one tab in 500ml of water to support immune function as you rehydrate. The members of the Nod-like receptor (NLR) family can form multi-protein complexes called inflammasomes that regulate the secretion of pro-inflammatory cytokines like IL-1β [63]. IL-1β is a key mediator of inflammation and is known to be a major protective cytokine against S. aureus infection [64]. However, increased production of IL-1β can also aggravate GVHD pathophysiology [65]. Studies have identified different inflammasome pathways like Nlrp1, Nlrp3 and Ipaf. Apart from their role in infection, the inflammasomes have been linked to pyroptosis and autophagy [63]. Additionally, the Nlrp3 inflammasome is known to mediate the adjuvanticity of alum [66], [67]. The role of the inflammasome in wound healing is also becoming increasingly apparent [68]– [70].

This approach gives you confidence that SIS pay attention to detail and deliver high quality sports nutrition, whether you are an elite athlete or just trying to keep fit and healthy A–C): Effect of HKSA-SIS-H exposure on the expression of inflammatory cytokines and chemokines involved in wound healing and GVHD. Data for each group used in the figure are based on fold change values obtained by comparing to the PBS control group. (*= p<0.05, **= p<0.01 and ***= p<0.001). Something to also consider is the amount of caffeine you want in your energy source. Caffeine has been proven to boost mental and physical performance when undertaking Isotonic exercise, making it a great ingredient option. However, it is not necessary for everyone. So take your own health and needs into consideration.Finance is subject to application, financial circumstances and borrowing history. Performance Cycling Limited FRN: 720557 trading as Tredz are authorised and regulated by the Financial Conduct Authority. We are a credit broker not a lender – credit is subject to status and affordability and is provided by Mitsubishi HC Capital UK PLC. Terms & Conditions Apply. Vitamin C (200mg) and Iron (2.5mg) are known to contribute to the maintenance of the normal function of the immune system during and after intense physical exercise in addition to your RDA.